Faculty
Faculty Publications
Counterintuitive relationship between visceral fat and all‐cause mortality in an elderly Asian population | |
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Year of publication | 2015 |
Title of paper | Counterintuitive relationship between visceral fat and all‐cause mortality in an elderly Asian population |
Author | Eun Shil Hong Ah Reum Khang Eun Roh Eu Jeong Ku Ye An Kim Kyoung Min Kim Jae Hoon Moon Sung Hee Choi Kyong Soo Park Ki Woong Kim Hak Chul Jang Soo Lim |
Publication in journal | Obesity |
Status of publication | accepted |
Vol | 23(1) |
Link | https://onlinelibrary.wiley.com/doi/full/10.1002/oby.20914 289회 연결 |
ObjectiveAbdominal obesity is considered to be a risk factor for mortality. However, recent studies indicate that overweight may be negatively associated with mortality (“obesity paradox”). The relationships between mortality and various obesity markers in an elderly Asian cohort were evaluated. MethodsSubjects of the Korean Longitudinal Study on Health and Aging (KLoSHA) (n = 1000, age ≥65 years) were included. The visceral fat area (VFA) and subcutaneous fat area (SFA) were measured using computed tomography. ResultsA total of 222 deaths occurred during the 6‐year follow‐up (median = 5.2 [range 0.1–6.3] years). Body mass index (BMI), VFA, SFA, and total fat mass were negatively associated with all‐cause mortality in the univariable analyses (hazard ratio [HR] 0.67 per 1 SD [95% CI 0.57‐0.77], 0.66 [0.55‐0.79], 0.73 [0.61‐0.86], and 0.74 [0.63‐0.87], respectively). BMI and VFA were significantly associated with all‐cause mortality in the multivariable analyses (HR 0.85 per 1 SD [95% CI 0.73‐0.99] and 0.64 [0.47‐0.87], respectively). When stratified by quartiles, the HR associated with VFA was the lowest in the third quartile. ConclusionsIn this observational study with a short follow‐up of elderly Asian people, higher amounts of visceral fat, a marker for central obesity, were associated with decreased all‐cause mortality. |