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Association of Central Serous Chorioretinopathy with Psychosocial Factors is Dependent on Its Phase and Subtype
Year of publication 2018
Title of paper Association of Central Serous Chorioretinopathy with Psychosocial Factors is Dependent on Its Phase and Subtype
Author Yong-Kyu Kim, Se Joon Woo, Kyu Hyung Park, Yeon Kyung Chi, Ji Won Han, and Ki Woong Kim
Publication in journal Korean Journal of Opthalmology
Status of publication accepted
Vol 32(4)
Link https://www.ncbi.nlm.nih.gov/pubmed/30091306 196회 연결

Purpose

To analyze the psychosocial factors associated with central serous chorioretinopathy (CSC) according to its phases and subtypes and to correlate the factors with the extent of choroidal hyperpermeability.

Methods

Age- and sex-matched CSC patients and controls (n = 37 in each group) were enrolled, and their psychosocial factors were compared. CSC was divided into two phases (active and inactive), and active CSC was further divided into two subtypes (acute and chronic). The correlations between the size of the hyperpermeable choroidal lesion identified on indocyanine green angiography and psychosocial factors were examined.

Results

Active CSC patients experienced more stressful events (p = 0.030), were more depressive (p = 0.037), and felt less emotional (p = 0.014) and informational (p = 0.014) support than the matched controls, whereas inactive CSC patients were comparable to the matched controls in all psychosocial factors. Among the active CSC patients, acute patients were more depressive (p = 0.029), while chronic patients experienced more stressful events (p = 0.024) than their matched controls. The size of the hyperpermeable choroidal lesion was correlated with the severity of depression in acute patients.

Conclusions

Association of CSC with psychosocial factors was dependent on the phase and subtype of CSC. Psychosocial factors were associated with CSC in the active phase, and severity of depression was correlated with the size of the choroidal pathology in acute active CSC. Further prospective studies to investigate if psychosocial factors can trigger CSC are warranted.

Keywords: Anxiety, Central serous chorioretinopathy, Choroid, Depression, Psychological stress